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TRAcP

The TRAcP Mouse Monoclonal Antibody [Clone ZM174] is designed to specifically detect Tartrate-Resistant Acid Phosphatase (TRAcP), also known as acid phosphatase 5 (ACP5). TRAcP is a lysosomal enzyme prominently expressed in osteoclasts, activated macrophages, and dendritic cells. It serves as a histochemical marker of bone resorption and is also associated with certain hematologic malignancies and histiocytic disorders. Clone ZM174 provides strong, specific nuclear and cytoplasmic staining in formalin-fixed, paraffin-embedded (FFPE) tissues. It is ideal for identifying osteoclasts in bone tissue and characterizing myeloid lineage tumors.

Specifications

Species Reactivity

Humans; others not tested

Known Applications

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As

Buffer with protein carrier and preservative

Storage

Store at 2ºC to 8ºC

Control

Hairy cell leukemia

Visualization

Cytoplasmic

Isotype

IgG2b /κ

Immunogen

Recombinant full-length human ACP5 protein

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G2486RP