The TRIM29 Mouse Monoclonal Antibody [Clone TRIM29/1041] is a high-affinity reagent developed for the detection of TRIM29, a member of the tripartite motif-containing (TRIM) protein family. This protein is implicated in DNA damage response, tumor progression, and cell proliferation, and has been identified as a useful immunohistochemical marker for lung squamous cell carcinoma (SqCC). Clone TRIM29/1041 delivers strong and specific nuclear and/or cytoplasmic staining in formalin-fixed, paraffin-embedded (FFPE) tissues. This antibody is particularly valuable in differentiating lung squamous cell carcinoma from other non-small cell lung cancer (NSCLC) subtypes, aiding in accurate subtyping and diagnostic precision.
Mouse
Recombinant human TRIM29 protein fragment (amino acids approximately 1-150)
TRIM29/1041
IgG2a, kappa
Human. Others not known.
A431 cells. Tonsil or Squamous cell carcinoma.
This antibody recognizes a 66kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29).
Cytoplasmic & Cell Surface