Fighting Cancer, One Slide at a Time

Product Overview

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replicationdependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Specifications

Source

Rabbit

Isotype

IgG

Purification

Affinity purification

Storage

Store at -20℃. Avoid freeze / thaw cycles.

Observed MW

17kd

Calculated MW

16kDa

Category

SMab Recombinant Monoclonal Antibody

Applications

WB,IHCP,IF/ICC,IP,ChIP,ELISA,DB,CUT&Tag

Cross-Reactivity

Human,Mouse,Rat,Other (Wide Range Predicted)

Clone number

GR54169

Immunogen

A synthetic trimethylated peptide around K27 of human Histone H3 (NP_003520.1).

Synonyms

H3t; H3.4; H3/g; H3FT; H3C16; HIST3H3; TriMethyl-Histone H3-K27

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G22006RP