Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replicationdependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Rabbit
IgG
Affinity purification
Store at -20℃. Avoid freeze / thaw cycles.
17kd
16kDa
SMab Recombinant Monoclonal Antibody
WB,IHCP,IF/ICC,IP,ChIP,ELISA,DB,CUT&Tag
Human,Mouse,Rat,Other (Wide Range Predicted)
GR54169
A synthetic trimethylated peptide around K27 of human Histone H3 (NP_003520.1).
H3t; H3.4; H3/g; H3FT; H3C16; HIST3H3; TriMethyl-Histone H3-K27