Fighting Cancer, One Slide at a Time

Product Overview

Vascular Endothelial Growth Factor (VEGF) belongs to the platelet-derived growth factor family, specifically the cystine-knot growth factors. VEGF plays a crucial role in vasculogenesis (formation of the embryonic circulatory system) and angiogenesis (development of new blood vessels from existing vasculature). Elevated VEGF expression has been associated with reduced survival rates in certain cancers.

Immunohistochemical Methodology

The detection of antigens in tissues and cells involves a multi-step immunohistochemical process: 1. The primary antibody binds to its specific antigenic site.
2. An enzyme-labeled polymer is then applied to bind the primary antibody.
3. The presence of the bound antibody is visualized through a colorimetric reaction.

INTENDED USE

For research purposes only. Not intended for diagnostic use.

Specifications

Source

Rabbit monoclonal

Species Reactivity

Human

Clone

EP1176Y

Isotype

IgG

Antigen

VEGF

Cellular Localization

Cell membrane and/or cytoplasm

Positive Tissue Control

Tonsil, certain breast and ovarian cancers

Total Protein Concentration

Approximately 10 mg/mL (contact for lot-specific Ig concentration)

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G356RP