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Product Overview

GR155/Rabbit/Monoclonal

Villin GR155 is a rabbit monoclonal antibody that specifically targets villin, an actin-binding protein predominantly expressed in the brush border of epithelial cells in the gastrointestinal tract, kidney, and other absorptive tissues. Produced using recombinant technology, the ZR155 clone provides high specificity and strong affinity, making it a valuable tool for detecting villin in various biological and clinical research applications. Villin plays a crucial role in the maintenance of microvilli structure and function, as well as in epithelial cell differentiation and motility. The rabbit origin of this monoclonal antibody enhances its sensitivity, making it particularly effective in immunohistochemistry (IHC), where it is commonly used to identify epithelial origin in tumors, especially in distinguishing metastatic carcinomas of gastrointestinal origin. The Villin ZR155 antibody is widely utilized in pathology and cancer diagnostics, aiding in the classification of tumors and the assessment of tissue morphology.

Specifications

Species Reactivity

Humans; others not tested

Known Applications

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As

Buffer with protein carrier and preservative

Storage

Store at 2ºC to 8ºC

Control

Colon carcinoma, small intestine

Visualization

Cytoplasmic

Isotype

IgG

Immunogen

Recombinant human Villin fragment (around aa179-311)

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G2491RP