Product Overview
GR381/Rabbit/Monoclonal
Vimentin GR381 is a rabbit monoclonal antibody designed to specifically recognize vimentin, a structural protein of the type III intermediate filament family that is predominantly expressed in mesenchymal cells. The ZR381 clone is produced using advanced recombinant antibody technology, offering high affinity and specificity, which makes it highly reliable for use in immunohistochemistry (IHC), western blotting, and other immunodetection techniques. Vimentin plays a crucial role in maintaining cellular architecture, supporting organelle positioning, and facilitating cellular processes such as migration, signaling, and division. Clinically, vimentin is widely used as a biomarker for mesenchymal origin and is essential in diagnosing sarcomas, as well as in identifying epithelial-to-mesenchymal transition (EMT) in carcinomas—a process associated with cancer progression and metastasis. The rabbit monoclonal nature of ZR381 provides enhanced sensitivity and clearer staining in formalin-fixed, paraffin-embedded tissue samples, making it a valuable tool in both research and diagnostic pathology.
