The gene TMEM16A, also known as TMEM16 FLJ10261, ANO1, ORAOV2, and AOS2, which is located on chromosome 11q13.1, codes for the calcium-dependent chloride channel protein DOG1. DOG1 performs a number of essential roles, including controlling the cholinergic activity of gastrointestinal smooth muscle , and regulating cell survival and proliferation. In the identification of gastrointestinal stromal tumors (GIST), anti-DOG1 antibody has been proven to be helpful.
| Volume: | Catalog No: |
|---|---|
| Concentrated 0.1 mL | G0244 A |
| Concentrated 0.5 mL | G0244 B |
| Concentrated 1 mL | G0244 C |
| Prediluted 6.0 mL | G0244 AA |
| Prediluted 3.0 mL | G0244 BB |
| Species | Rabbit |
|---|---|
| Clone | SP31 |
| Visualisation | Cytoplasmic, Membranous |
| Control | Gastrointestinal Stromal Tumor (Cytoplasmic, Membranous) |
| Intended Use | RUO |
