The Mouse Monoclonal SOX11 antibody, clone CLO142, is a highly specific antibody designed to detect the SOX11 protein, a transcription factor belonging to the SOX (SRY-related HMG-box) family. This antibody is produced using hybridoma technology, where mice are immunized with a peptide or recombinant fragment of SOX11, leading to the generation of a single clone—CLO142—that produces uniform antibodies against a specific epitope on the SOX11 protein. SOX11 is known for its role in embryonic development and neurogenesis, and it has also been identified as a diagnostic marker in certain cancers, particularly mantle cell lymphoma (MCL). The CLO142 clone is widely used in diagnostic pathology and research, particularly in applications such as immunohistochemistry (IHC), Western blotting, and immunocytochemistry, due to its strong affinity and specificity. It is an essential tool for investigating SOX11 expression patterns in both normal and pathological tissues.
Mouse
IgG2a
Monoclonal
CL0142
Liquid
Recombinant Fragment Protein within Human SOX11 aa 50-200.
Human; others not tested
Nuclear